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What if you had been a problem drinker or alcoholic, as well as a medical professional could give you a drug to look at away your urge to drink—while you are still permitted to continue drinking? Advocates of the treatment approach, referred to as the Sinclair method, claim you'd likely experience no withdrawal symptoms. According to proponents, after three to four months around the medication, all while still being in a position to continue to drink, you'd experience diminished cravings or even find that your urge to drink disappears. Using two separate drugs to shed weight can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you should err on the side of caution and permit the FDA do its job and demand some study be done so the public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies come in business to generate money and that they would say anything to keep people on their medications. Researchers discovered that participants investing in this drug for any year, lost excess weight within 4 weeks and have kept the weight off during the entire 56 weeks of the study. Contrave can be a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of multiple active ingredient, which might make them far better and safer. Combo-pilling is the newest fad or also the newest in the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is now popular could be the fact that since right now there aren't long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and must not be taken in people who have seizure disorders. The drug also can raise hypertension and heartbeat, and really should not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure levels and heartrate and must not be used in patients with uncontrolled high blood pressure level, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients for the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking. The most common negative effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.